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The Disease Encyclopedia.
Sunday, April 10, 2016
Thursday, May 14, 2015
GOOD NEWS!!! NEW TREATMENT COULD CURE ASTHMA COMPLETELY!!!!
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Scientists discover asthma's potential root cause and a novel treatment
Cardiff scientists have for the first time identified the potential root cause of asthma and an existing drug that offers a new treatment.
Published today in Science Translational Medicine journal, University researchers, working in collaboration with scientists at King's College London and the Mayo Clinic (USA), describe the previously unproven role of the calcium sensing receptor (CaSR) in causing asthma, a disease which affects 300 million people worldwide.
The team used mouse models of asthma and human airway tissue from asthmatic and non-asthmatic people to reach their findings.
Crucially, the paper highlights the effectiveness of a class of drugs known as calcilytics in manipulating CaSR to reverse all symptoms associated with the condition. These symptoms include airway narrowing, airway twitchiness and inflammation - all of which contribute to increased breathing difficulty.
"Our findings are incredibly exciting," said the principal investigator, Professor Daniela Riccardi, from the School of Biosciences. "For the first time we have found a link airways inflammation, which can be caused by environmental triggers - such as allergens, cigarette smoke and car fumes – and airways twitchiness in allergic asthma.
"Our paper shows how these triggers release chemicals that activate CaSR in airway tissue and drive asthma symptoms like airway twitchiness, inflammation, and narrowing. Using calcilytics, nebulized directly into the lungs, we show that it is possible to deactivate CaSR and prevent all of these symptoms."
Dr Samantha Walker, Director of Research and Policy at Asthma UK, who helped fund the research, said:
"This hugely exciting discovery enables us, for the first time, to tackle the underlying causes of asthma symptoms. Five per cent of people with asthma don't respond to current treatments so research breakthroughs could be life changing for hundreds of thousands of people.
"If this research proves successful we may be just a few years away from a new treatment for asthma, and we urgently need further investment to take it further through clinical trials. Asthma research is chronically underfunded; there have only been a handful of new treatments developed in the last 50 years so the importance of investment in research like this is absolutely essential."
While asthma is well controlled in some people, around one-in-twelve patients respond poorly to current treatments. This significant minority accounts for around 90% of healthcare costs associated with the condition.
According to Cardiff Professor Paul Kemp, who co-authored the study, the identification of CaSR in airway tissue means that the potential for treatment of other inflammatory lung diseases beyond asthma is immense. These include chronic obstructive pulmonary disease (COPD) and chronic bronchitis, for which currently there exists no cure. It is predicted that by 2020 these diseases will be the third biggest killers worldwide.Professor Riccardi and her collaborators are now seeking funding to determine the efficacy of calcilytic drugs in treating asthmas that are especially difficult to treat, particularly steroid-resistant and influenza-exacerbated asthma, and to test these drugs in patients with asthma.
Calcilytics were first developed for the treatment of osteoporosis around 15 years ago with the aim of strengthening deteriorating bone by targeting CaSR to induce the release of an anabolic hormone. Although clinically safe and well tolerated in people, calcilytics proved unsuccessful in treating osteoporosis.
But this latest breakthrough has provided researchers with the unique opportunity to re-purpose these drugs, potentially accelerating the time it takes for them to be approved for use asthma patients. Once funding has been secured, the group aim to be trialling the drugs on humans within two years.
"If we can prove that calcilytics are safe when administered directly to the lung in people, then in five years we could be in a position to treat patients and potentially stop asthma from happening in the first place," added Professor Riccardi.
The study was part-funded by Asthma UK, the Cardiff Partnership Fund and a BBSRC 'Sparking Impact' award.
Scientists discover asthma's potential root cause and a novel treatment
Cardiff scientists have for the first time identified the potential root cause of asthma and an existing drug that offers a new treatment.
Published today in Science Translational Medicine journal, University researchers, working in collaboration with scientists at King's College London and the Mayo Clinic (USA), describe the previously unproven role of the calcium sensing receptor (CaSR) in causing asthma, a disease which affects 300 million people worldwide.
The team used mouse models of asthma and human airway tissue from asthmatic and non-asthmatic people to reach their findings.
Crucially, the paper highlights the effectiveness of a class of drugs known as calcilytics in manipulating CaSR to reverse all symptoms associated with the condition. These symptoms include airway narrowing, airway twitchiness and inflammation - all of which contribute to increased breathing difficulty.
"Our findings are incredibly exciting," said the principal investigator, Professor Daniela Riccardi, from the School of Biosciences. "For the first time we have found a link airways inflammation, which can be caused by environmental triggers - such as allergens, cigarette smoke and car fumes – and airways twitchiness in allergic asthma.
"Our paper shows how these triggers release chemicals that activate CaSR in airway tissue and drive asthma symptoms like airway twitchiness, inflammation, and narrowing. Using calcilytics, nebulized directly into the lungs, we show that it is possible to deactivate CaSR and prevent all of these symptoms."
Dr Samantha Walker, Director of Research and Policy at Asthma UK, who helped fund the research, said:
"This hugely exciting discovery enables us, for the first time, to tackle the underlying causes of asthma symptoms. Five per cent of people with asthma don't respond to current treatments so research breakthroughs could be life changing for hundreds of thousands of people.
"If this research proves successful we may be just a few years away from a new treatment for asthma, and we urgently need further investment to take it further through clinical trials. Asthma research is chronically underfunded; there have only been a handful of new treatments developed in the last 50 years so the importance of investment in research like this is absolutely essential."
While asthma is well controlled in some people, around one-in-twelve patients respond poorly to current treatments. This significant minority accounts for around 90% of healthcare costs associated with the condition.
According to Cardiff Professor Paul Kemp, who co-authored the study, the identification of CaSR in airway tissue means that the potential for treatment of other inflammatory lung diseases beyond asthma is immense. These include chronic obstructive pulmonary disease (COPD) and chronic bronchitis, for which currently there exists no cure. It is predicted that by 2020 these diseases will be the third biggest killers worldwide.Professor Riccardi and her collaborators are now seeking funding to determine the efficacy of calcilytic drugs in treating asthmas that are especially difficult to treat, particularly steroid-resistant and influenza-exacerbated asthma, and to test these drugs in patients with asthma.
Calcilytics were first developed for the treatment of osteoporosis around 15 years ago with the aim of strengthening deteriorating bone by targeting CaSR to induce the release of an anabolic hormone. Although clinically safe and well tolerated in people, calcilytics proved unsuccessful in treating osteoporosis.
But this latest breakthrough has provided researchers with the unique opportunity to re-purpose these drugs, potentially accelerating the time it takes for them to be approved for use asthma patients. Once funding has been secured, the group aim to be trialling the drugs on humans within two years.
"If we can prove that calcilytics are safe when administered directly to the lung in people, then in five years we could be in a position to treat patients and potentially stop asthma from happening in the first place," added Professor Riccardi.
The study was part-funded by Asthma UK, the Cardiff Partnership Fund and a BBSRC 'Sparking Impact' award.
Monday, April 27, 2015
Air Travelling Frequently??? Here Are Tips to keep your Ear Safe.
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Ear problems are the most common medical complaint of airplane travelers, and while they are usually simple, minor annoyances, they may result in temporary pain and hearing loss. Make air travel comfortable by learning how to equalize the pressure in the ears instead of suffering from an uncomfortable feeling of fullness or pressure.
WHY DO EARS POP?
Normally, swallowing causes a little click or popping sound in the ear. This occurs because a small bubble of air has entered the middle ear, up from the back of the nose. It passes through the Eustachian tube, a membrane-lined tube about the size of a pencil lead that connects the back of the nose with the middle ear. The air in the middle ear is constantly being absorbed by its membranous lining and re-supplied through the Eustachian tube. In this manner, air pressure on both sides of the eardrum stays about equal. If, and when, the air pressure is not equal the ear feels blocked.
The Eustachian tube can be blocked, or obstructed, for a variety of reasons. When that occurs, the middle ear pressure cannot be equalized. The air already there is absorbed and a vacuum occurs, sucking the eardrum inward and stretching it. Such an eardrum cannot vibrate naturally, so sounds are muffled or blocked, and the stretching can be painful. If the tube remains blocked, fluid (like blood serum) will seep into the area from the membranes in an attempt to overcome the vacuum. This is called fluid in the ear, serous otitis or aero-otitis. Uncommon problems include developing a hole in the ear drum, hearing loss and dizziness.
The most common cause for a blocked Eustachian tube is the common cold. Sinus infections and nasal allergies are also common causes. A stuffy nose leads to stuffy ears because the swollen membranes block the opening of the Eustachian tube.
The most common cause for a blocked Eustachian tube is the common cold. Sinus infections and nasal allergies are also common causes. A stuffy nose leads to stuffy ears because the swollen membranes block the opening of the Eustachian tube.
HOW CAN AIR TRAVEL CAUSE HEARING PROBLEMS?
Air travel is sometimes associated with rapid changes in air pressure. To maintain comfort, the Eustachian tube must open frequently and wide enough to equalize the changes in pressure. This is especially true when the airplane is landing, going from low atmospheric pressure down closer to earth where the air pressure is higher.
Actually, any situation in which rapid altitude or pressure changes occur creates the problem. It may be experienced when riding in elevators or when diving to the bottom of a swimming pool. Deep sea divers, as well as pilots, are taught how to equalize their ear pressure. Anybody can learn the trick too.
HOW TO UNBLOCK EARS?
Swallowing activates the muscles that open the Eustachian tube. Swallowing occurs more often when chewing gum or when sucking on hard candies. These are good air travel practices, especially just before take-off and during descent. Yawning is even better. Avoid sleeping during descent because swallowing may not occur often enough to keep up with the pressure changes.
During decent, if yawning and swallowing are not effective, pinch the nostrils shut, take a mouthful of air, and direct the air into the back of the nose as if trying to blow the nose gently, you should feel a pressure buildup but do not let the air out your mouth The ears have been successfully unblocked when a pop is heard. This may have to be repeated several times during descent.
During decent, if yawning and swallowing are not effective, pinch the nostrils shut, take a mouthful of air, and direct the air into the back of the nose as if trying to blow the nose gently, you should feel a pressure buildup but do not let the air out your mouth The ears have been successfully unblocked when a pop is heard. This may have to be repeated several times during descent.
Even after landing, continue the pressure equalizing techniques and the use of decongestants and nasal sprays. If the ears fail to open or if pain persists, seek the help of a physician who has experience in the care of ear disorders. The ear specialist may need to release the pressure or fluid with a small incision in the ear drum.
For some people, these techniques may not work. If you fly frequently and have chronic issues with pressure or pain, you doctor may recommend placing small pressure equalization tubes.
HOW TO HELP BABIES UNBLOCK THEIR EARS?
Babies cannot intentionally pop their ears, but popping may occur if they are sucking on a bottle or pacifier. Feed the baby during the flight, and do not allow him or her to sleep during descent. Children are especially vulnerable to blockages because their Eustachian tubes are narrower than in adults.
IS THE USE OF DECONGESTANTS AND NOSE SPRAYS RECOMMENDED?
Many experienced air travelers use a decongestant pill or an over the counter nasal spray an hour or so before descent. This will shrink the membranes and help the ears pop more easily. Travelers with allergy problems should take their medication at the beginning of the flight for the same reason. However, avoid making a habit of over the counter nasal sprays. After a few days, they may cause more congestion than relief.
Decongestant tablets and sprays can be purchased without a prescription. However, they should be avoided by people with heart disease, high blood pressure, irregular heart rhythms, thyroid disease, or excessive nervousness. Such people should consult their physicians before using these medicines. Pregnant women should likewise consult their physicians first.
Tips to prevent discomfort during air travel
- Consult with your surgeon on how soon after ear surgery it is safe to fly.
- Postpone an airplane trip if a cold, sinus infection, or an allergy attack is present.
- Patients in good health can take a decongestant pill or nose spray approximately an hour before descent to help the ears pop more easily.
- Avoid sleeping during descent.
- Chew gum or suck on a hard candy just before take-off and during descent.
- When inflating the ears, do not use excessive force. The proper technique involves only pressure created by the cheek and throat muscles.
- These tips may also be used for people who scuba dive.
Sore Throat- Facts you should know.
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Infections from viruses or bacteria are the main cause of sore throats and can make it difficult to talk and breathe. Allergies and sinus infections can also contribute to a sore throat. If you have a sore throat that lasts for more than five to seven days, you should see your doctor. While increasing your liquid intake, gargling with warm salt water, or taking over-the-counter pain relievers may help, if appropriate, your doctor may write you a prescription for an antibiotic.
WHAT ARE THE CAUSES AND SYMPTOMS OF A SORE THROAT?
Infections by contagious viruses or bacteria are the source of the majority of sore throats.
Viruses: Sore throats often accompany viral infections, including the flu, colds, measles, chicken pox, whooping cough, and croup. One viral infection, infectious mononucleosis, or mono, takes much longer than a week to be cured. This virus lodges in the lymph system, causing massive enlargement of the tonsils, with white patches on their surface. Other symptoms include swollen glands in the neck, armpits, and groin; fever, chills, and headache. If you are suffering from mono, you will likely experience a severe sore throat that may last for one to four weeks and, sometimes, serious breathing difficulties. Mono causes extreme fatigue that can last six weeks or more, and can also affect the liver, leading to jaundice-yellow skin and eyes.
Bacteria: Strep throat is an infection caused by a particular strain of streptococcus bacteria. This infection can also damage the heart valves (rheumatic fever) and kidneys (nephritis), cause scarlet fever, tonsillitis, pneumonia, sinusitis, and ear infections. Symptoms of strep throat often include fever (greater than 101°F), white draining patches on the throat, and swollen or tender lymph glands in the neck. Children may have a headache and stomach pain.
Tonsillitis is an infection of the lumpy-appearing lymphatic tissues on each side of the back of the throat.
Infections in the nose and sinuses also can cause sore throats, because mucus from the nose drains down into the throat and carries the infection with it.
The most dangerous throat infection is epiglottitis, which infects a portion of the larynx (voice box) and causes swelling that closes the airway. Epiglottitis is an emergency condition that requires prompt medical attention. Suspect it when swallowing is extremely painful (causing drooling), when speech is muffled, and when breathing becomes difficult. Epiglottitis may not be obvious just by looking in the mouth. A strep test may overlook this infection.
OTHER CAUSES
Allergies to pollens and molds such as cat and dog dander and house dust are common causes of sore throats.
Irritation caused by dry heat, a chronic stuffy nose, pollutants and chemicals, and straining your voice can also irritate your throat.
Reflux, or a regurgitation of stomach acids up into the back of the throat, can cause you to wake up with a sore throat.
Tumors of the throat, tongue, and larynx (voice box) can cause a sore throat with pain radiating to the ear and/or difficulty swallowing. Other important symptoms can include hoarseness, noisy breathing, a lump in the neck, unexplained weight loss, and/or spitting up blood in the saliva or phlegm.
HIV infection can sometimes cause a chronic sore throat, due not to HIV itself but to a secondary infection that can be extremely serious.
WHEN SHOULD I SEE A DOCTOR?
Whenever a sore throat is severe, persists longer than the usual five-to-seven day duration of a cold or flu, and is not associated with an avoidable allergy or irritation, you should seek medical attention. The following signs and symptoms should alert you to see your physician:
- Severe and prolonged sore throat
- Difficulty breathing
- Difficulty swallowing
- Difficulty opening the mouth
- Joint pain
- Earache
- Rash
- Fever (over 101°)
- Blood in saliva or phlegm
- Frequently recurring sore throat
- Lump in neck
- Hoarseness lasting over two weeks
HOW WILL I BE TESTED FOR A SORE THROAT?
To test for strep throat, your doctor may want to do a throat culture, a non-surgical procedure that uses an instrument to take a sampling of the infected cells. Because the culture will not detect other infections, when it is negative, your physician will base his/her decision for treatment on the severity of your symptoms and the appearance of your throat on examination.
WHAT ARE MY TREATMENT OPTIONS?
A mild sore throat associated with cold or flu symptoms can be made more comfortable with the following remedies:
- Increase your liquid intake.
- Warm tea with honey is a favorite home remedy.
- Use a steamer or humidifier in your bedroom.
- Gargle with warm salt water several times daily: ¼ tsp. salt to ½ cup water.
- Take over-the-counter pain relievers such as acetaminophen (Tylenol Sore Throat®, Tempra®) or ibuprofen (Motrin IB®, Advil®).
If you have a bacterial infection your doctor will prescribe an antibiotic to alleviate your symptoms. Antibiotics are drugs that kill or impair bacteria. Penicillin or erythromycin (well-known antibiotics) are prescribed when the physician suspects streptococcal or another bacterial infection that responds to them. However, a number of bacterial throat infections require other antibiotics instead.
Antibiotics do not cure viral infections, but viruses do lower the patients resistance to bacterial infections. When such a combined infection occurs, antibiotics may be recommended. When an antibiotic is prescribed, it should be taken as the physician directs for the full course (usually 7-10 days). Otherwise the infection may not be completely eliminated, and could return. Some children will experience recurrent infection despite antibiotic treatment. When some of these are strep infections or are severe, your child may be a candidate for a tonsillectomy.
HOW CAN I PREVENT A SORE THROAT?
- Avoid smoking or exposure to secondhand smoke. Tobacco smoke, whether primary or secondary, contains hundreds of toxic chemicals that can irritate the throat lining.
- If you have seasonal allergies or ongoing allergic reactions to dust, molds, or pet dander, youre more likely to develop a sore throat than people who dont have allergies.
- Avoid exposure to chemical irritants. Particulate matter in the air from the burning of fossil fuels, as well as common household chemicals, can cause throat irritation.
- If you experience chronic or frequent sinus infections you are more likely to experience a sore throat, since drainage from nose or sinus infections can cause throat infections as well.
- If you live or work in close quarters such as a child care center, classroom, office, prison, or military installation, you are at greater risk because viral and bacterial infections spread easily in environments where people are in close proximity.
- Maintain good hygiene. Do not share napkins, towels, and utensils with an infected person. Wash your hands regularly with soap or a sanitizing gel, for 10-15 seconds.
If you have HIV or diabetes, are undergoing steroid treatment or chemotherapy, are experiencing extreme fatigue or have a poor diet, you have reduced immunity and are more susceptible to infections.
Sinusitis
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Sinusitis means your sinuses are inflamed. The cause can be an infection or another problem. Your sinuses are hollow air spaces within the bones surrounding the nose. They produce mucus, which drains into the nose.
If your nose is swollen, this can block the sinuses and cause pain.
There are several types of sinusitis, including
- Acute, which lasts up to 4 weeks
- Subacute, which lasts 4 to 12 weeks
- Chronic, which lasts more than 12 weeks and can continue for months or even years
- Recurrent, with several attacks within a year
Acute sinusitis often starts as a cold, which then turns into a bacterial infection. Allergies, nasal problems, and certain diseases can also cause acute and chronic sinusitis.
Symptoms of sinusitis can include fever, weakness, fatigue, cough, and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip. Your health care professional diagnoses sinusitis based on your symptoms and an examination of your nose and face. You may also need imaging tests.
Treatments include antibiotics, decongestants, and pain relievers. Using heat pads on the inflamed area, saline nasal sprays, and vaporizers can also help.
Sunday, April 26, 2015
Chest Clinics: ASTHMA- SYMPTOMS, DIAGNOSIS, TRIGGERS
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Pulmonary Medicine Blog By Dr Deepu
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Chest Clinics: 7 healthy ways for a healthy life!!!
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Thursday, April 23, 2015
Secondhand Smoke: A Danger to Millions
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Despite falling smoking rates, 58 million nonsmokers in the United States, including 15 million children ages 3 to 11 years, are still exposed to secondhand tobacco smoke. Recent research shows that although secondhand smoke exposure rates in 2011–2012 had dropped for all population groups, some groups continue to be exposed at much higher rates than others. In addition to children, these include Black nonsmokers, people who live below the poverty level, and those who rent housing. Among all nonsmokers in the United States, 1 in 4 is exposed to secondhand smoke.
Secondhand smoke contains dangerous chemicals that are known to cause heart disease, stroke, and lung cancer in adults and ear infections, respiratory infections, asthma attacks, and sudden infant death syndrome (SIDS) in infants and children. Since 1964, two and a half million nonsmokers have died from diseases caused by exposure to secondhand smoke; every year, secondhand smoke kills 41,000 adult nonsmokers from heart disease and lung cancer and 400 babies from SIDS.
Lung Cancer
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Lung cancer is the leading cause of cancer death and the second most common cancer among both men and women in the United States.
The most important thing you can do to lower your lung cancer risk is to quit smoking and avoid secondhand smoke.For help quitting, visit smokefree.gov,
The second leading cause of lung cancer is radon, a naturally occurring gas that comes from rocks and dirt and can get trapped in houses and buildings. Get your home tested for radon.
Basic Information About Lung Cancer
Cancer is a disease in which cells in the body grow out of control. When cancer starts in the lungs, it is called lung cancer.
Lung cancer is the leading cause of cancer death and the second most diagnosed cancer in both men and women in the United States. In 2011, 14% of all cancer diagnoses and 27% of all cancer deaths were due to lung cancer. After increasing for decades, lung cancer rates are decreasing nationally, as fewer people smoke cigarettes.
Cigarette smoking is the number one cause of lung cancer. Lung cancer also can be caused by using other types of tobacco (such as pipes or cigars), breathing secondhand smoke, being exposed to substances such as asbestos or radon at home or work, and having a family history of lung cancer.
What Is Lung Cancer?
Cancer is a disease in which cells in the body grow out of control. When cancer starts in the lungs, it is calledlung cancer.
Lung cancer begins in the lungs and may spread to lymph nodes or other organs in the body, such as the brain. Cancer from other organs also may spread to the lungs. When cancer cells spread from one organ to another, they are called metastases.
Lung cancers usually are grouped into two main types called small cell and non-small cell. These types of lung cancer grow differently and are treated differently. Non-small cell lung cancer is more common than small cell lung cancer. For more information, visit the National Cancer Institute’s Lung Cancer.
What Are the Risk Factors for Lung Cancer?
Research has found several risk factors that may increase your chances of getting lung cancer.
Smoking
Cigarette smoking is the number one risk factor for lung cancer. In the United States, cigarette smoking is linked to about 90% of lung cancers. Using other tobacco products such as cigars or pipes also increases the risk for lung cancer. Tobacco smoke is a toxic mix of more than 7,000 chemicals. Many are poisons. At least 70 are known to cause cancer in people or animals.
People who smoke cigarettes are 15 to 30 times more likely to get lung cancer or die from lung cancer than people who do not smoke. Even smoking a few cigarettes a day or smoking occasionally increases the risk of lung cancer. The more years a person smokes and the more cigarettes smoked each day, the more risk goes up.
People who quit smoking have a lower risk of lung cancer than if they had continued to smoke, but their risk is higher than the risk for people who never smoked. Quitting smoking at any age can lower the risk of lung cancer.
Cigarette smoking can cause cancer almost anywhere in the body. Cigarette smoking causes cancers of the lung, mouth, nose, throat, voicebox (larynx), esophagus, liver, bladder, kidney, pancreas, colon, rectum, cervix, stomach, blood, and bone marrow (acute myeloid leukemia).
Secondhand Smoke
Smoke from other people’s cigarettes, pipes, or cigars (secondhand smoke) also causes lung cancer. When a person breathes in secondhand smoke, it is like he or she is smoking. In the United States, two out of five adults who don’t smoke and half of children are exposed to secondhand smoke, and about 7,300 people who never smoked die from lung cancer due to secondhand smoke every year.
Radon
Radon is a naturally occurring gas that comes from rocks and dirt and can get trapped in houses and buildings. It cannot be seen, tasted, or smelled. According to the U.S. Environmental Protection Agency (EPA), radon causes about 20,000 cases of lung cancer each year, making it the second leading cause of lung cancer. Nearly one out of every 15 homes in the U.S. is thought to have high radon levels. The EPA recommends testing homes for radon and using proven ways to lower high radon levels.
Other Substances
Examples of substances found at some workplaces that increase risk include asbestos, arsenic, diesel exhaust, and some forms of silica and chromium. For many of these substances, the risk of getting lung cancer is even higher for those who smoke.
Personal or Family History of Lung Cancer
If you are a lung cancer survivor, there is a risk that you may develop another lung cancer, especially if you smoke. Your risk of lung cancer may be higher if your parents, brothers or sisters, or children have had lung cancer. This could be true because they also smoke, or they live or work in the same place where they are exposed to radon and other substances that can cause lung cancer.
Radiation Therapy to the Chest
Cancer survivors who had radiation therapy to the chest are at higher risk of lung cancer.
Diet
Scientists are studying many different foods and dietary supplements to see whether they change the risk of getting lung cancer. There is much we still need to know. We do know that smokers who take beta-carotene supplements have increased risk of lung cancer. For more information, visit Lung Cancer Prevention.
Also, arsenic in drinking water (primarily from private wells) can increase the risk of lung cancer. For more information, visit the EPA’s Arsenic in Drinking Water.
What Are the Symptoms of Lung Cancer?
Different people have different symptoms for lung cancer. Some people have symptoms related to the lungs. Some people whose lung cancer has spread to other parts of the body (metastasized) have symptoms specific to that part of the body. Some people just have general symptoms of not feeling well. Most people with lung cancer don't have symptoms until the cancer is advanced. Lung cancer symptoms may include—
- Coughing that gets worse or doesn’t go away.
- Chest pain.
- Shortness of breath.
- Wheezing.
- Coughing up blood.
- Feeling very tired all the time.
- Weight loss with no known cause.
Other changes that can sometimes occur with lung cancer may include repeated bouts of pneumonia and swollen or enlarged lymph nodes (glands) inside the chest in the area between the lungs.
These symptoms can happen with other illnesses, too. If you have some of these symptoms, talk to your doctor, who can help find the cause.
What Can I Do to Reduce My Risk of Lung Cancer?
You can help lower your risk of lung cancer in the following ways—
- Don’t smoke. Cigarette smoking causes about 90% of lung cancer deaths in the United States. The most important thing you can do to prevent lung cancer is to not start smoking, or to quit if you smoke.
- Avoid secondhand smoke. Smoke from other people’s cigarettes, cigars, or pipes is called secondhand smoke. Make your home and car smoke-free.
- Get your home tested for radon. The U.S. Environmental Protection Agency recommends that all homes be tested for radon.
What Screening Tests Are There?
Screening means testing for a disease when there are no symptoms or history of that disease. Doctors recommend a screening test to find a disease early, when treatment may work better.
The only recommended screening test for lung cancer is low-dose computed tomography (also called a low-dose CT scan, or LDCT). In this test, an X-ray machine scans the body and uses low doses of radiation to make detailed pictures of the lungs.
Who Should Be Screened?
The U.S. Preventive Services Task Force recommends yearly lung cancer screening with LDCT for people who—
- Have a history of heavy smoking, and
- Smoke now or have quit within the past 15 years, and
- Are between 55 and 80 years old.
Heavy smoking means a smoking history of 30 pack years or more. A pack year is smoking an average of one pack of cigarettes per day for one year. For example, a person could have a 30 pack-year history by smoking one pack a day for 30 years or two packs a day for 15 years.
Risks of Screening
Lung cancer screening has at least three risks—
- A lung cancer screening test can suggest that a person has lung cancer when no cancer is present. This is called a false-positive result. False-positive results can lead to follow-up tests and surgeries that are not needed and may have more risks.
- A lung cancer screening test can find cases of cancer that may never have caused a problem for the patient. This is called overdiagnosis. Overdiagnosis can lead to treatment that is not needed.
- Radiation from repeated LDCT tests can cause cancer in otherwise healthy people.
That is why lung cancer screening is recommended only for adults who have no symptoms but who are at high risk for developing the disease because of their smoking history and age.
If you are thinking about getting screened, talk to your doctor. If lung cancer screening is right for you, your doctor can refer you to a high-quality treatment facility.
The best way to reduce your risk of lung cancer is to not smoke and to avoid secondhand smoke. Lung cancer screening is not a substitute for quitting smoking.
When Should Screening Stop?
The Task Force recommends that yearly lung cancer screening stop when the person being screened—
- Turns 81 years old, or
- Has not smoked in 15 years, or
How Is Lung Cancer Diagnosed and Treated?
Types of Lung Cancer
There two main types of lung cancer are small cell lung cancer and non-small cell lung cancer. These categories refer to what the cancer cells look like under a microscope. Non-small cell lung cancer is more common than small cell lung cancer.
Staging
If lung cancer is diagnosed, other tests are done to find out how far it has spread through the lungs, lymph nodes, and the rest of the body. This process is called staging. The type and stage of lung cancer tells doctors what kind of treatment you need. For more information, visit Stages of Non-Small Cell Lung Cancer and Stages of Small Cell Lung Cancer.
Types of Treatment
Lung cancer is treated in several ways, depending on the type of lung cancer and how far it has spread. People with non-small cell lung cancer can be treated with surgery, chemotherapy, radiation therapy, targeted therapy, or a combination of these treatments. People with small cell lung cancer are usually treated with radiation therapy and chemotherapy.
- Surgery. An operation where doctors cut out cancer tissue.
- Chemotherapy. Using special medicines to shrink or kill the cancer. The drugs can be pills you take or medicines given in your veins, or sometimes both.
- Radiation therapy. Using high-energy rays (similar to X-rays) to kill the cancer.
- Targeted therapy. Using drugs to block the growth and spread of cancer cells. The drugs can be pills you take or medicines given in your veins.
Doctors from different specialties often work together to treat lung cancer. Pulmonologists are doctors who are experts in diseases of the lungs. Surgeonsare doctors who perform operations. Thoracic surgeons specialize in chest, heart, and lung surgery. Medical oncologists are doctors who treat cancer with medicines. Radiation oncologists are doctors who treat cancers with radiation.
Birth Defects
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Birth defects are serious conditions that are changes to the structure of one or more parts of the body. Birth defects affect 1 in every 33 babies born in the United States each year.1 Read more about what we have learned about birth defects and how women can improve their chances of having a baby born without a birth defect.
Birth Defects Are Common
Every 4 ½ minutes, a baby is born with a birth defect in the United States. That translates into nearly 120,000 babies affected by birth defects each year.1
Birth defects can affect almost any part of the body (e.g., heart, brain, foot). They may affect how the body looks, works, or both. Birth defects can vary from mild to severe. The well-being of each child affected with a birth defect depends mostly on
Avian Influenza In Humans ( Bird flu)
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Avian Influenza A Virus Infections in Humans
Although avian influenza A viruses usually do not infect humans, rare cases of human infection with these viruses have been reported. Most human infections with avian influenza A viruses have occurred following direct or close contact with infected poultry. Illness in humans has ranged from mild to severe.
The spread of avian influenza A viruses from one ill person to another has been reported very rarely, and has been limited, inefficient and not sustained. However, because of the possibility that avian influenza A viruses could change and gain the ability to spread easily between people, monitoring for human infection and person-to-person
Arthritis
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Definition
Although the word arthritis actually means joint inflammation, we use the term arthritis in the public health world to describe more than 100 rheumatic diseases and conditions that affect joints, the tissues which surround the joint and other connective tissue. The pattern, severity and location of symptoms can vary depending on the specific form of the disease. Typically, rheumatic conditions are characterized by pain and stiffness in and around one or more joints. The symptoms can develop gradually or
Wednesday, April 22, 2015
Sleep Deprivation and Deficiency
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Sleep deprivation (DEP-rih-VA-shun) is a condition that occurs if you don't get enough sleep. Sleep deficiency is a broader concept. It occurs if you have one or more of the following:
- You don't get enough sleep (sleep deprivation)
- You sleep at the wrong time of day (that is, you're out of sync with your body's natural clock)
- You don't sleep well or get all of the different types of sleep that your body needs
- You have a sleep disorder that prevents you from getting enough sleep or causes poor quality sleep
This article focuses on sleep deficiency, unless otherwise noted.
Sleeping is a basic human need,
Sleep Apnea
Hello Welcome to the Blog" Health Advise MD " This information is intended for personal use and should not be taken as health advise. Please consult your doctor if you have this problem.
Sleep apnea (AP-ne-ah) is a common disorder in which you have one or more pauses in breathing or shallow breaths while you sleep.
Breathing pauses can last from a few seconds to minutes. They may occur 30 times or more an hour. Typically, normal breathing then starts again, sometimes with a loud snort or choking sound.
Sleep apnea usually is a chronic (ongoing) condition that disrupts your sleep. When your breathing pauses or becomes shallow,
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